Susceptibilidade antimicrobiana ao metronidazol de microrganismos isolados de periodontite crônica e agressiva

Autores

  • Diego Costa Ahern
  • Christiane Marie Schweitzer
  • Alvimar Lima de Castro
  • Gilberto Aparecido Coclete
  • Ana Claudia Okamoto
  • Elerson Gaetti-Jardim Jr

Resumo

O objetivo deste estudo foi avaliar a suscetibilidade microbiana ao metronidazol de microrganismos isolados de pacientes com periodontite crônica ou agressiva. As amostras foram obtidas de 50 pacientes com periodontite e os microorganismos foram isolados em meios de cultura seletivos e não seletivos e identificados por métodos bioquímicos e testados para susceptibilidade ao metronidazol. Os resultados evidenciaram a susceptibilidade ao metronidazol entre Gram-negativos anaeróbios e alguns susceptibilidade intermediária e resistência entre os Gram-positivos anaeróbios e facultativos.

Palavras Chave: Periodontite, Bactérias, Metronidazol, Testes de Sensibilidade Microbiana.

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Referências

Braga RRR, Carvalho MAR, Brunã-Romero O, Teixeira RE, Costa JE, Mendes EN et al. Quantification of five putative periodontal pathogens in female patients with and without chronic periodontitis by real-time polymerase chain reaction. Anaerobe. 2010; 16: 234-9.

Armitage GC. Comparison of the microbiological features of chronic and aggressive periodontitis. Periodontol 2000. 2010; 53: 70–88.

Gaetti-JardimJr E, Okamoto AC, Melo ME, Schweitzer CM. Opportunistic microorganisms in patients with head and neck trauma. Arch Health Invest. 2013; 2(1): 16-23.

Ramos MMB, Mendonça MR, Pellizzer EP, Okamoto AC, Gaetti-Jardim Jr E. Associação entre a doença periodontal e doenças sistêmicas crônicas – reisão de literatura. Arch Health Invest. 2013; 2(1): 24-31.

Cunha RF, Machado AC, Watanabe S, Freire IR, Goiato MC, Gaetti-Jardim Jr E. A combination of clinical and microbiological management of generalized aggressive periodontitis in primary teeth. A case report. Int J Paediat Dent. 2012; 22(4): 310–6.

Ahuja A, Baiju CS, Ahuja V. Role of antibiotics in generalized aggressive periodontitis: a review of clinical trials in humans. J Indian Soc Periodontol. 2012; 16(3): 317-23.

Eick S, Straube A, Guentsch A, Pfister W, Jentsch H. Comparison of real-time polymerase chain reaction and DNA-strip technology in microbiological evaluation of periodontitis treatment. Diag Microbiol Infect Dis. 2011; 69: 12-20.

Senhorinho GNA, Nakano V, Liu C, Song Y, Finegold S, Avila-Campos MJ. Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis. Anaerobe. 2012; 18: 381-5.

Gaetti-Jardim Jr E, Landucci LF, Lins SA, Vieira EMM, Oliveira SR. Susceptibility of strict and facultative anaerobes isolated from endodontic infections to metronidazole and β-lactams. J Appl Oral Sci. 2007; 15(6): 539-45.

Narikawa S. Distribution of metronidazole sucecptibility factors in obligate anaerobes. J Antimicrob Chemother. 1986; 18(5): 565-74.

Gaetti-Jardim Jr E, Monti LM, Ciesielski FIN, Gaetti-Jardim EC, Okamoto AC, Schweitzer CM, et al. Subgingival microbiota from Cebus apella (capuchin monkey) with different periodontal conditions. Anaerobe. 2012 18(3):263-9.doi 10.1016/.

Clinical and Laboratory Standards Institute. Methods for antimicrobial susceptibility testing of anaerobic bacteria: approved standard, CLSI document M11-A7. Wayne, PA: Clinical and Laboratory Standards Institute; 2007.

Baumgartner JC, Xia T. Antibiotic susceptibility of bacteria associated with endodontic abscesses. J Endod. 2003; 29(1): 44-7.

Kuriyama T, Karasawa T, Nakagawa K, Nakamura S, Yamamoto E. Antimicrobial susceptibility of major pathogens of orofacial odontogenic infections to 11 β-lactam antibiotics. Oral Microbiol Immunol. 2002; 17: 285-9.

Ramos MMB, Gaetti-Jardim EC, Gaetti-Jardim Jr E. Resistance to tetracycline and β-lactams and distribution of resistance markers in enteric microorganisms and pseudomonads isolated from the oral cavity. J Appl Oral Sci. 2009; 17 Suppl: 13-8.

Gaetti-Jardim EC, Marqueti AC, Faverani LP, Gaetti-Jarim Jr E. Antimicrobial resistance of aerobes and facultative anaerobes isolated from the oral cavity. J Appl Oral Sci. 2010; 18(6): 551-9.

Casarin RCV, Ribeiro EP, Sallum EA, Nociti Jr FH, Gonçalves RB, Casati MZ. The combination of amoxicillin and metronidazole improves clinical and microbiologic results of one-stage, full-mouth, ultrasonic debridement in aggressive periodontitis treatment. J Periodontol. 2012; 83: 988-98.

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Publicado

2014-03-06

Como Citar

Ahern, D. C., Schweitzer, C. M., Castro, A. L. de, Coclete, G. A., Okamoto, A. C., & Gaetti-Jardim Jr, E. (2014). Susceptibilidade antimicrobiana ao metronidazol de microrganismos isolados de periodontite crônica e agressiva. ARCHIVES OF HEALTH INVESTIGATION, 3(1). Recuperado de https://archhealthinvestigation.emnuvens.com.br/ArcHI/article/view/204

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