General aspects of Treacher Collins Syndrome and its impacts on quality of life: literature review
DOI:
https://doi.org/10.21270/archi.v10i9.5047Keywords:
Mandibulofacial Dysostosis, Craniofacial Abnormalities, Quality of LifeAbstract
Treacher Collins Syndrome is an autosomal dominant development disorder that occurs due to TCOF1 gene mutation. The objective of this research was to approach a general overview about Treacher Collins Syndrome, through a literature review, high lighting the main clinical symptoms and their consequences in the affected individual's quality of life in differents cenarios. For this, a literature review was carried out, based on analysis and data collection, through the digital databases: Sciello, PubMed and Lilacs. It turns out that the anomaly under study has a variable expressiveness, being able to manifest alterations respiratory, masticatory, ophthalmological and hearing, due The mutations in the first and second branchial arc. This picture makes individuals with the syndrome more likely to develop psychological problems not only due to the existing social prejudices, but also the complex and multiprofessional treatment in which they should be submitted for better living conditions.
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References
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