Evaluation of Tenosynovial Giant Cell Tumor in Hand and Wrist

Authors

  • Sérgio Luis Cavalcante Ibiapina Programa de Residência Médica de Ortopedia e Traumatologia da Universidade Federal do Ceará (UFC), 60440-900 Fortaleza – CE, Brasil
  • Mateus Torres Muniz Médico Residente do Programa de Cirurgião de Mão do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (HC-FMRP-USP) 14049-900 Ribeirão Preto – SP, Brasil https://orcid.org/0000-0001-9502-8732
  • Gabriel Mattos Goes Médico Residente do Programa de Cirurgião de Mão do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (HC-FMRP-USP) 14049-900 Ribeirão Preto – SP, Brasil https://orcid.org/0000-0002-5806-7334
  • Rafael Romano Rahal Médico Residente do Programa de Cirurgião de Mão do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (HC-FMRP-USP) 14049-900 Ribeirão Preto – SP, Brasil https://orcid.org/0000-0002-7222-5714
  • Luis Guilherme Rosifini Alves Rezende Médico Assistente do Serviço da Cirurgião de Mão do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (HC-FMRP-USP) 14049-900 Ribeirão Preto – SP, Brasil https://orcid.org/0000-0002-2037-0135
  • Filipe Jun Shimaoka Médico Assistente do Serviço da Cirurgião de Mão do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (HC-FMRP-USP) 14049-900 Ribeirão Preto – SP, Brasil
  • Nilton Mazzer Professor Titular e Chefe do Serviço da Cirurgião de Mão do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (HC-FMRP-USP) 14049-900 Ribeirão Preto – SP, Brasil

DOI:

https://doi.org/10.21270/archi.v11i5.5931

Keywords:

Giant Cell Tumor of Tendon Sheath, Neoplasms, Margins of Excision

Abstract

Synovial sheath giant cell tumors (GCT) are the second most common hand tumor type. They are prevalent in middle-aged women, and details about their recurrence rate remain unclear. The aim of this study is to evaluate the prevalence of GCT and its recurrence regarding the involvement of the margins in the biopsies. Methods: a retrospective study evaluating 48 patients with GCT who underwent surgical treatment by excision. Results: 70% of these patients, 66% in the right upper limb, and recurrence rate of 8.3%, with a tendency (p=0.074) for affected margins. Conclusion: Despite the impairment of the margins being a factor that characterizes its recurrence, further studies are needed to determine other associated factors.

Downloads

Download data is not yet available.

References

Flandry F, Hughston JC. Pigmented villonodular synovitis. J Bone Joint Surg Am. 1987;69(6):942-49.

Kitagawa Y, Takai S. Optimal Treatment for Tenosynovial Giant Cell Tumor of the Hand. J Nippon Med Sch. 2020;87(4):184-90.

Froimson AI. Benign solid tumors. Hand Clin 1987;3(2):213-17.

Glowacki KA, Weiss AP. Giant cell tumors of tendon sheath. Hand Clin. 1995;11(2):245-53.

Hansen P, Nielsen PT, Wahlin AB. Pigmented villonodular synovitis of the extensor tendon sheaths in a child. J Hand Surg Br. 1988;13(3):313-14.

Jaffe HL, LLichtenstein L, Sutro CJ. Pigmented villonodular synovitis, bursitis, and tenosynovitis. Arch Pathol. 1941;31:731-65.

Reilly KE, Stern PJ, Dale JA. Recurrent giant cell tumors of the tendon sheath. J Hand Surg Am. 1999;24(6):1298-302.

Ho CY, Maleki Z. Giant cell tumor of tendon sheath: cytomorphologic and radiologic findings in 41 patients. Diagn Cytopathol. 2012;40 Suppl 2:E94-8.

Al-Qattan MM. Giant cell tumours of tendon sheath: classification and recurrence rate. J Hand Surg Br. 2001;26(1):72-5.

Aubain Somerhausen N de St, Dal Cin P. Giant cell tumor of tendon sheath. In:Fletcher CDM, Unni KK, Mertens F, eds. World Health Organization classification of tumours. Tumours of soft tissue and bone. Lyon: IARC press; 2002. pp. 110-111.

Gouin F, Noailles T. Localized and diffuse forms of tenosynovial giant cell tumor (formerly giant cell tumor of the tendon sheath and pigmented villonodular synovitis). Orthop Traumatol Surg Res. 2017;103(1S):S91-S97.

Ushijima M, Hashimoto H, Tsuneyoshi M, Enjoji M. Giant cell tumor of the tendon sheath (nodular tenosynovitis). A study of 207 cases to compare the large joint group with the common digit group. Cancer. 1986;57(4):875-84.

Botez P, Sirbu PD, Grierosu C, Mihailescu D, Savin L, Scarlat MM. Adult multifocal pigmented villonodular synovitis--clinical review. Int Orthop. 2013;37(4):729-33.

Weiss SW, Goldblum JR, Folpe AL. Enzinger andWeiss’s soft tissue tumors. 6 th ed. Philadelphia: Saunders; 2014

Adams EL, Yoder EM, Kasdan ML. Giant cell tumor of the tendon sheath: experience with 65 cases. Eplasty. 2012;12:e50.

Lautenbach M, Kim S, Millrose M, Eisenschenk A. Nodular giant cell tumour of the tendon sheath of the hand: analysis of eighty-four cases: diagnostic decisions and outcome. Int Orthop. 2013;37(11):2211-215.

Di Grazia S, Succi G, Fragetta F, Perrotta RE. Giant cell tumor of tendon sheath: study of 64 cases and review of literature. G Chir. 2013; 34(5-6):149-52.

Hwang JS, Fitzhugh VA, Gibson PD, Didesch J, Ahmed I. Multiple Giant Cell Tumors of Tendon Sheath Found within a Single Digit of a 9-Year-Old. Case Rep Orthop. 2016;2016:1834740.

Fotiadis E, Papadopoulos A, Svarnas T, Akritopoulos P, Sachinis NP, Chalidis BE. Giant cell tumour of tendon sheath of the digits. A systematic review. Hand (NY). 2011;6(3):244-49.

Fyfe IS, MacFarlane AU. Pigmented villonodular synovitis of the hand. Hand. 1980;12(2):179-88.

Williams J, Hodari A, Janevski P, Siddiqui A. Recurrence of giant cell tumors in the hand: a prospective study. J Hand Surg Am. 2010;35(3):451-56.

Koutserimpas C, Kastanis G, Ioannidis A, Filippou D, Balalis K. Giant cell tumors of the tendon sheath of the hand: an 11-year retrospective study. J BUON. 2018;23(5):1546-51.

Ozben H, Coskun T. Giant cell tumor of tendon sheath in the hand: analysis of risk factors for recurrence in 50 cases. BMC Musculoskelet Disord. 2019;20(1):457.

Wang JP, Rancy SK, DiCarlo EF, Wolfe SW. Recurrent pigmented villonodular synovitis and multifocal giant cell tumor of the tendon sheath: case report. J Hand Surg Am. 2015;40(3): 537-41.

Downloads

Published

2022-10-10

How to Cite

Ibiapina, S. L. C., Muniz, M. T., Goes, G. M., Rahal, R. R., Rezende, L. G. R. A., Shimaoka, F. J., & Mazzer, N. (2022). Evaluation of Tenosynovial Giant Cell Tumor in Hand and Wrist. ARCHIVES OF HEALTH INVESTIGATION, 11(5), 866–870. https://doi.org/10.21270/archi.v11i5.5931

Issue

Vol. 11 No. 5 (2022)

Section

Original Articles