Alternativa terapeutica para el tratamiento de liquen plano oral con localización inusual: reporte de caso
DOI:
https://doi.org/10.21270/archi.v10i5.4970Palabras clave:
Liquen Plano, Liquen Plano Oral, Labio, Preparaciones FarmacéuticasResumen
El liquen plano oral (LPO) es considerada una lesión potencialmente maligna (LPM), aunque su tasa de transformación sea aún controversial. Recientemente fueron introducidos nuevos tratamientos como ser; glicocorticoides en combinación con calcipotriol (análogo de la vitamina D3). Lesiones labiales aisladas pueden responder positivamente a esta terapia tópica combinada, aumentando la efectividad del tratamiento. Por tanto, el objetivo de este reporte de caso es mostrar una alternativa terapéutica para lesiones labiales aisladas y persistentes de LPO. Se realizó un examen clínico de una lesión de labio inferior con aproximadamente 10 años de evolución en un paciente de 18 años, el cual reveló múltiples áreas eritematosas delimitadas por finas estrías blanquecinas localizadas en el bermellón del labio inferior. No se observaron anomalías en mucosa oral, piel, uñas, o cuero cabelludo. El examen microscópico de la biopsia incisional mostró áreas de degeneración de la camada basal con intenso infiltrado inflamatorio mononuclear em banda predominantemente subepitelial. La propuesta terapéutica fue la aplicación de Daivobet®; combinación tópica de corticoide y análogo de la vitamina D3. Luego de quince días las lesiones fueron evaluadas nuevamente constatando remisión de estas, la medicación fue suspendida e indicada cuando se presentase recidiva. Durante el seguimiento del caso no se observaron complicaciones. La combinación de estos componentes puede ser una nueva alternativa para el tratamiento de LPO.
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