Multicenter investigation of predictors to self-report vaccination and seroprotection against Hepatitis B among healthcare workers
DOI:
https://doi.org/10.21270/archi.v10i8.5216Palabras clave:
Hepatitis B, Vacunación, Immunización, Personal de SaludResumen
Objetivo: Los profesionales de la salud trabajan con exposición a riesgos laborales por el virus de la hepatitis B (VHB). El estado de vacunación se ha explorado ampliamente; sin embargo, pocas investigaciones han confirmado la inmunidad al VHB mediante pruebas serológicas. Material y método: Realizamos un estudio multicéntrico basado en un enfoque dual para comprender los predictores de la vacunación contra el VHB y la seroprotección entre los profesionales de la salud. Se diseñó un estudio transversal entre 371 trabajadores del estado de Alagoas (Brasil); todos ellos del servicio de salud pública. Construimos un modelo de regresión de Poisson múltiple utilizando la vacunación y la seroprotección como factores dependientes. Resultados: La vacunación autoinformada total fue del 70,4% y la confirmación por respuesta inmune fue del 72,2%. Tres predictores se asociaron con la vacunación: nivel educativo; uso de equipo de protección personal durante el trabajo y evaluación serológica individual. Dos predictores se asociaron a la seroprotección: nivel educativo y uso de equipo de protección durante el trabajo. Conclusión: Nuestros hallazgos señalaron que casi un tercio de los profesionales de la salud no estaban inmunizados contra el VHB, y aporta alguna evidencia de que factores como la educación y el uso de equipo de protección personal pueden predecir la susceptibilidad al VHB.
Descargas
Citas
Mast EE, Margolis HS, Fiore AE, Brink EW, Goldstein ST, Wang SA. A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP) part 1: immunization of infants, children, and adolescents. MMWM Recomm Rep. 2005;54(RR-16):1-31.
Morowatishaifabad M, Sakhvidi MJ, Gholianavval M, Boroujeni DM, Alavijeh MM. Predictors of hepatitis B preventive behavioral intentions in healthcare workers. Saf Health Work. 2015;6(2):139-42.
Assunção AA, Araújo TM, Ribeiro RB, Oliveira SV. Hepatitis B vaccination and occupation exposure in the healthcare sector in Belo Horizonte, Southeastern Brazil. Rev Saude Publica. 2012;46(4):665-73.
Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de DST, Aids e Hepatites Virais. O manual técnico para o diagnóstico das hepatites virais. Brasília: MS 2015. 68p.
Department of Health & Human Services. Centers for Disease Control and Prevention – CDC. Division of Viral. Interpretation of hepatitis B serological test results. [cited 2018 Dec 5]. Available from: https://www.cdc.gov/hepatitis/
hbv/hbvfaq.htm.
Abebaw TA, Aderaw Z, Gebremichael B. Hepatitis B virus vaccination status and associated factors among health care workers in Shashemene Zonal Town, Shashemene, Ethiopia: a cross sectional study. BMC Res Notes. 2017;6(10):260.
Akibu M, Nurgi S, Tadese M, Tsega WD. Attitude and vaccination status of healthcare workers against hepatitis B infection in a teaching hospital, Ethiopia. Scientifica. 2018;ID:6705305. 8p.
Batra V, Goswami A, Dadhich S, Kothari D, Bhargava N. Hepatitis B immunization in healthcare workers. Annals of Gastroenterology. 2015;28(2):276-80.
World Health Organization. Hepatitis B, Fact sheet No. 204, updated July 2018. Available from: http://www.who.int/mediacentre/ factsheets/fs204/en/.
Pereira LM, Martelli CM, Merchán-Hamann E, Montarroyos UR, Braga MC, Lima ML et al. Population-Based multicentric survey of Hepatitis b infection and risk factor differences among three regions in Brazil. Am J Trop Med Hyg. 2009;81(2):240-47.
Contera-Moreno L, Andrade SM, Cury Pontes ER, Stief AC, Pompilio MA, Motta-Castro AR. Hepatitis B virus infection in a population exposed to occupational hazards: firefighters of a metropolitan region in central Brazil. Rev Soc Bras Med Trop. 2012;45(4):463-67.
Petruzziello A. Epidemiology of hepatitis B virus (HBV) and hepatitis C virus (HCV) related hepatocellular carcinoma. Open Virol J. 2018;12(Suppl-1, M3):26-32.
Aaron D, Nagu TJ, Rwegasha J, Komba E. Hepatitis B vaccination coverage among healthcare workers at national hospital in Tanzania: how much, who and why? BMC Infect Dis. 2017;17:786.
Bonanni P, Bonaccorsi G. Vaccination against Hepatitis B in health care workers. Vaccine. 2001;19(17-19):2389-94.
Ziglam H, El-Hattab M, Shingheer N, Zorgani A, Elahmer O. Hepatitis B vaccination status among healthcare workers in a tertiary care hospital in Tripoli, Libya. J Infect Public Health. 2013;6(4):246-51.
Chang MH, Chen DS. Prevention of hepatitis B. Cold Spring Harb Perspect Med. 2015;5:a021-493.
Divisão de Imunização. Vacina contra hepatite B. Rev Saúde Pública. 2006;40(6):1137-40.
Brasil. Ministério da Saúde. Secretaria de Políticas de Saúde. Programa Nacional de Hepatites Virais. Brasília: Ministério da Saúde, 2002. 64p.
Marques CC, Carvalheiro JR. Assessment of laboratory diagnostic network in the implementation of the Program for Viral Hepatitis Prevention and Control in São Paulo State, Brazil, 1997-2012. Epidemiol. Serv. Saude. 2017;26(3):513-24.
Andrade Neto EP, Dutra CS, Lima V, Goes P. Prevalence of occupational accidents and vaccination profile against hepatitis B between students and dental professionals: a pilot study. Arq Odontol. 2013;49(1):32-8.
Oliveira LC, Pontes JP. Frequency of hepatitis B immunity and occupational exposures to body fluids among brazilian medical students at a public university. Rev Inst Med Trop. 2010;52(5):247-51.
Instituto Brasileiro de Geografia e Estatística – IBGE. IBGE Cidades Alagoas. Available from: https://cidades.ibge.gov.br/brasil/al/panorama.
Governo do Estado de Alagoas. Secretaria de Estado da Saúde – Sesau. Unidades e Serviços. Available from: http://www.saude.al. gov.br/acesso-a-informacao/130-2/.
Garcia LP, Facchini LA. Hepatitis B vaccination among primary healthcare workers. Cad Saúde Pública. 2008;24(5):1130-140.
Stroffolini T, Petrosillo N, Ippolito G, Lopalco A, Sagliocca L, Adamo B. Hepatitis B vaccination coverage among healthcare workers in Italy. Infect Control Hosp Epidemiol. 1998;19(10):789-91.
Costa FM, Lima Martins AM, Santos Neto PE, Veloso DN, Magalhães VS, Ferreira RC. Is vaccination against hepatitis B a reality among primary health care workers? Rev Latino-Am Enfermagem. 2013;21(1):316-24.
Burmett RJ, François G, Mphahlele MJ, Mureithi JG, Africa PN, Satekge MM, et al. Hepatitis B vaccination coverage in healthcare workers in Gauteng Province, South Africa. Vaccine. 2011;29(25):4293-97.
Rossato EM, Ferreira J. Perforating injuries and vaccination against hepatitis B among health workers in the Municipality of Santa Rosa, State of Rio Grande do Sul, Brazil, 2008.
Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Programa Nacional de Imunizações. Coberturas vacinais no Brasil período: 2010 - 2014. Brasília: Ministério da Saúde, 2015. 31p.
Souza FO, Freitas PS, Araújo TM, Gomes MR. Hepatitis B and Anti-HBS vaccination among health workers. Cad Saúde Colet. 2015;23(2):172-79.
Souza FO, Araújo TM. Occupational exposure and hepatitis B vaccination among health care workers. Rev Bras Med Trab. 2018;16(1):36-43.