Efficacy of Photodynamic Therapy as an Adjunct to Endodontic Treatment
DOI:
https://doi.org/10.21270/archi.v15i5.6783Keywords:
Photochemotherapy, Photodynamic Therapy, Endodontics, Endodontic TreatmentAbstract
Introduction: Dental caries and lesions lead to pulp damage and the need for endodontic treatment. Limitations in bacterial elimination motivate adjunctive therapies. Photodynamic therapy shows effective antimicrobial potential in improving endodontic success. Objective: To investigate the efficacy of photodynamic therapy as an adjunct to conventional endodontic treatment. Materials and Methods: This review was based on the PICO strategy and developed through searches in the PubMed, SciELO, and BVS databases, following rigorous inclusion and exclusion criteria to answer the guiding research question. Randomized clinical trials addressing the chosen topic, published in the last 10 years in Portuguese, English, and Spanish, with available abstracts and full texts, were included. Books, theses, monographs, dissertations, letters to the editor, and literature reviews (integrative or systematic), as well as texts not related to the review topic and duplicate articles, were excluded. Results: A total of 1,686 articles were identified: 399 in PubMed, 1,267 in BVS, and 20 in SciELO. Of these, 1,675 were excluded after applying the eligibility criteria, leaving 11 articles which underwent detailed data extraction to compose the bibliographic repertoire of this study. Conclusion: Photodynamic therapy emerges as a promising adjunctive technique in the biomechanical preparation of root canals, reducing the microbial population within them and contributing to the success of endodontic treatment in both permanent and primary teeth.
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References
1. Costa-Santos L, et al. The effect of antimicrobial photodynamic therapy on infected dentin in primary teeth. Medicine. 2019;98(15):1-6.
2. Mota ACC, et al. Evaluation of the effectiveness of photodynamic therapy for the endodontic treatment of primary teeth: study protocol for a randomized controlled clinical trial. Trials. 2015;16:551.
3. Chen X, Liu X, Zhong J. Clinical and radiographic evaluation of pulpectomy in primary teeth: an 18-month randomized controlled trial. Head Face Med. 2017;13(12):1-10.
4. Priyadarshini P, et al. Clinical evaluation of instrumentation time and quality of obturation using paediatric hand and rotary file systems with conventional hand K-files for pulpectomy in primary mandibular molars: a double-blinded randomized controlled trial. Eur Arch Paediatr Dent. 2020;21(6):693-701.
5. Wince C, et al. Antimicrobial photodynamic therapy effects mediated by methylene blue in surfactant medium as an adjuvant treatment of teeth with apical periodontitis and presence of fistula: protocol for randomized controlled double-blind clinical trial. PLoS One. 2024;19(12):e0315169.
6. Lima SP, et al. Photodynamic therapy as an aiding in the endodontic treatment: case report. RGO Rev Gaúch Odontol. 2019;67:e20190030.
7. Catão MHCV, Batista ALA. In vitro evaluation of the antibacterial effect of photodynamic therapy with methylene blue. Pesqui Bras Odontopediatria Clin Integr. 2020;20:e4980.
8. Ramalho KM, et al. In vitro evaluation of methylene blue removal from root canal after photodynamic therapy. Photodiagnosis Photodyn Ther. 2017;20:248-252.
9. Miranda RG, Gusman HDS, Colombo APV. Antimicrobial efficacy of the EndoVac system plus PDT against intracanal Candida albicans: an ex vivo study. Braz Oral Res. 2015;29(1):1-7.
10. Fernandes MLMF, et al. Antimicrobial photodynamic therapy in the endodontic treatment of deciduous teeth: in vivo pilot study. Pesqui Bras Odontopediatria Clin Integr. 2020;20:e5309.
11. Okamoto CB, et al. Photodynamic therapy for endodontic treatment of primary teeth: a randomized controlled clinical trial. Photodiagnosis Photodyn Ther. 2020;30:101732.
12. Barazy R, et al. Can antimicrobial photodynamic therapy serve as an effective adjunct protocol for disinfecting the necrotic root canal system? A randomized controlled study. BDJ Open. 2024;10(1):53.
13. Ahangari Z, et al. Comparison of the antimicrobial efficacy of calcium hydroxide and photodynamic therapy against Enterococcus faecalis and Candida albicans in teeth with periapical lesions: an in vivo study. J Lasers Med Sci. 2017;8(2):72.
14. Asnaashari M, et al. A comparison between effect of photodynamic therapy by LED and calcium hydroxide therapy for root canal disinfection against Enterococcus faecalis: a randomized controlled trial. Photodiagnosis Photodyn Ther. 2017;17:226-232.
15. Dragana R, et al. Antibacterial efficiency of adjuvant photodynamic therapy and high-power diode laser in the treatment of young permanent teeth with chronic periapical periodontitis: a prospective clinical study. Photodiagnosis Photodyn Ther. 2023;41:103129.
16. Silva CC, et al. Antimicrobial photodynamic therapy associated with conventional endodontic treatment: a clinical and molecular microbiological study. Photochem Photobiol. 2018;94(2):351-356.
17. Miranda RG, Colombo APV. Clinical and microbiological effectiveness of photodynamic therapy on primary endodontic infections: a 6-month randomized clinical trial. Clin Oral Investig. 2018;22:1751-1761.
18. Rabello GD, et al. Does supplemental photodynamic therapy optimize the disinfection of bacteria and endotoxins in one-visit and two-visit root canal therapy? A randomized clinical trial. Photodiagnosis Photodyn Ther. 2017;19:205-211.
19. Alves-Silva EG, et al. Effect of antimicrobial photodynamic therapy on the reduction of bacteria and virulence factors in teeth with primary endodontic infection. Photodiagnosis Photodyn Ther. 2023;41:103292.
20. Moraes VG, et al. Impact of photobiomodulation during root canal treatment on oral health-related quality of life: a randomized clinical trial. Pesqui Bras Odontopediatria Clin Integr. 2024;24:e230064.
