Multidisciplinary assistance in the follow-up of patients with pemphigus vulgar
DOI:
https://doi.org/10.21270/archi.v10i9.5262Keywords:
Pemphigus, Skin Diseases, Vesiculobullous, Autoimmune DiseasesAbstract
The aim of this paper is report a case of a 33-year-old female patient, with the main complaint of multiple ulcerations in the oral mucosa, who had previously been diagnosed with pemphigus vulgaris, but due to the adverse effects of drug therapy, she abandoned the treatment. It was intent to the patient's adherence to treatment, with multiprofessional assistance, making her co-responsible for her clinical improvement. The therapy involved the topical use of 0.05% Clobetasol Propionate ointment and the systemic administration of Prednisone, achieving satisfactory results by the excellent clinical evolution.
Downloads
References
Griffiths C, Barker J, Bleiker T, Chalmers R, Creamer D. Rook's textbook of dermatology. 9. ed. Londres: Wiley Blackwell; 2016.
Feller L, Ballyram R, Khammissa RA, Altini M, Lemmer J. Immunopathogenic oral diseases: an overview focusing on pemphigus vulgaris and mucous membrane pemphigoid. Oral Health Prev Dent. 2017;15(2):177-82.
Baum S, Sakka N, Artsi O, Trau H, Barzilai A. Diagnosis and classification of autoimmune blistering diseases. Autoimmun. Rev. 2014;13(4-5):482-89.
Mcmillan R, Taylor J, Shephard M, Ahmed R, Carrozzo M, Setterfield J, et al. World Workshop on Oral Medicine VI: a systematic review of the treatment of mucocutaneous pemphigus vulgaris. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2015;120(2):132-42.
Ferreira VYN, Lyra TC, Pereira LL, Nascimento MAB, Souza LB, Bonan PRF. Eficácia do uso de corticosteroide sistêmico no tratamento do pênfigo vulgar oral. Arq ciênc saúde. 2016;23(3):10-13.
Madala J, Bashamalla R, Kumar MP. Conceitos atuais de pênfigo com uma visão profunda de seus aspectos moleculares. J Oral Maxillofac Pathol. 2017;21:260-63.
Ormond M, McParland H, Donaldson ANA, Andiappan M, Cook RJ, Escudier M et al. An Oral Disease Severity Score validated for use in oral pemphigus vulgaris. Br J Dermatol. 2018;179(4):872-81.
Kumar SJ, Nehru Anand SP, Gunasekaran N, Krishnan R. Oral pemphigus vulgaris: A case report with direct immunofluorescence study. J Oral Maxillofac Pathol. 2016;20(3):549.
Dimarco C. Pemphigus: Pathogenesis to Treatment. R. I. Med. J. 2016;99(12):28-31.
Santoro FA, Stoopler ET, Werth VP. Pemphigus. Dent Clin North Am. 2013;57(4): 1-20.
Batista MIBH, Paulino MR, Santos CAO, Andrade SC, Lima CA, Gueiros LA, et al. Correlação entre anti-desmogleína e lesões mucocutâneas em pacientes com pênfigo vulgar ou foliáceo. REFACS. 2019;7(1):16-22.
Saccucci M, Di Carlo G, Bossù M, Giovarruscio F, Salucci A, Polimeni A. Autoimmune Diseases and Their Manifestations on Oral Cavity: Diagnosis and Clinical Management. J. Immunol. Res. 2018;2018:6061825.
Arpita R, Monica A, Venkatesh N, Atul S, Varun M. Oral Pemphigus Vulgaris: Case Report. Ethiop. J. Health Sci. 2015;25(4):367-72.
Magliocca KR, Fitzpatrick SG. Autoimmune Disease Manifestations in the Oral Cavity. Surg. Pathol. Clin. 2016;10(1):57-88.
Kasperkiewicz M, Ellebrecht CT, Takahashi H, Yamagami J, Zillikens D, Payne AS, et al. Pemphigus. Nat Rev Dis Primers. 2017;11(3):17026.
Sankar V, Noujeim M. Oral Manifestations of Autoimmune and Connective Tissue Disorders. Atlas Oral Maxillofac Surg Clin North Am. 2017;25(2):113-26.
Sung JY, Roh MR, Kim SC. Quality of Life Assessment in Korean Patients With Pemphigus. Ann Dermatol. 2015;27(5):492-98.
Rao R, Srinivas CR. Counseling in pemphigus. Indian J Dermatol. 2017;62:279-81.
Hansen MS, Klefter ON, Julian HO, Pedersen AML, Heegaard S. Management of patients with ocular manifestations in vesiculobullous disorders affecting the mouth. Oral Dis. 2017; 23(7):849-53.
