Oral Manifestations and Dental Changes in Patientes with Sickle Cell Anemia: an Update
DOI:
https://doi.org/10.21270/archi.v12i3.5720Keywords:
Anemia, Sickle Cell, Oral Manifestations, Anemia, HemolyticAbstract
Sickle cell disease is an autosomal hereditary hemoglobinopathy in which a mutation in the beta chain of hemoglobin occurs. This mutation leads to a change in normal hemoglobin HbA, into hemoglobin C (HbC) or hemoglobin D (HbD) which implies tissue deoxygenation and sickling of red blood cells that determines their premature destruction and hemolytic anemia. The clinical characteristics of the disease vary in terms of pain episodes resulting from the vessel occlusion mechanism, organ damage and infections due to the severe condition of immunosuppression in these patients. Dental complications are of great relevance considering that these patients may present different kinds of oral manifestations and a dental infection complicated by a sickle cell crisis significantly increases the probability of hospital admission.
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